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Search Results for " West Nile virus "

ターゲット

阻害剤

天然化合物

リコンビナントタンパク質

カタログ番号	製品名	別名	ターゲット
T72041	Flaviviruses-IN-2		Virus Protease
	Flaviviruses-IN-2 is a potent flaviviruses inhibitor. Flaviviruses-IN-2 reduces West Nile virus (WNV) protease activity and inhibits WNV by 56%.		Virus Protease
T67777	Flaviviruses-IN-3	WAY-324593	Virus Protease
	Flaviviruses-IN-3 (compound 87) is a potent inhibitor of flaviviruse. Flaviviruses-IN-3 could reduce the WNV (West Nile virus) protease activity, with a inhibition of 54%.		Virus Protease
TNU0060	3’-O-Methyladenosine		Antiviral , Adenosine deaminase
	3’-O-Methyladenosine is an antiviral compound with inhibitory activity against West Nile Virus and can be used for the treatment of viral infections.3’-O-Methyladenosine inhibits adenosine deaminase type VII with a Ki va...		Antiviral , Adenosine deaminase
T4027	KIN1148		Influenza Virus
	KIN1148 is a novel small-molecule adjuvant that acts through the RIG-I pathway and IRF-3 transcription factor to stimulate inN/Ate immunity and protection following viral infection. The adjuvant will be developed for an ...		Influenza Virus
TNU0007	3'-Deoxy-3'-fluoroadenosine		Nucleoside Antimetabolite/Analog
	3'-Deoxy-3'-fluoroadenosine is a purine nucleoside analogue with a wide range of anti-tumor and anti-viral activity, and has inhibitory effects on tick-borne encephalitis virus (TBEV), Zika virus and West Nile virus (WNV...		Nucleoside Antimetabolite/Analog
T70855	Favipiravir sodium
	Favipiravir sodium is a selective inhibitor of viral RNA-dependent RNA polymerase with activity against many RNA viruses, influenza viruses, West Nile virus, yellow fever virus, foot-and-mouth disease virus as well as o...
T81309	RCB16007
	RCB16007 is a Yellow Fever Virus (YFV) inhibitor that also demonstrates inhibitory action against the West Nile virus with an effective concentration (EC50) of 7.9 μM and a cytotoxic concentration (CC50) of 17 μM [1].
T38861	Tat-beclin 1
	Tat-beclin 1, a peptide derived from the autophagy protein beclin 1, is a powerful inducer of autophagy. It interacts with GAPR-1 (GLIPR2), a negative regulator of autophagy. Tat-beclin 1 effectively reduces the buildup ...
T76058	Tat-beclin 1 TFA
	Tat-beclin 1 TFA, a peptide originating from a segment of the autophagy protein beclin 1, effectively initiates autophagy and engages with the autophagy negative regulator, GAPR-1 (GLIPR2). It notably reduces the buildup...

Compounds

Flaviviruses-IN-2

T72041

Synonym:

Target: Virus Protease

Flaviviruses-IN-3

T67777

Synonym: WAY-324593

Target: Virus Protease

3’-O-Methyladenosine

TNU0060

Synonym:

Target: Antiviral, Adenosine deaminase

KIN1148

T4027

Synonym:

Target: Influenza Virus

3'-Deoxy-3'-fluoroadenosine

TNU0007

Synonym:

Target: Nucleoside Antimetabolite/Analog

カタログ番号	製品名	別名	ターゲット
T2718	Palmatine chloride		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
	Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.		Others , Indoleamine 2,3-Dioxygenase (IDO) , Aurora Kinase
T5S0802	Palmatine	Berbericinine,Burasaine	Indoleamine 2,3-Dioxygenase (IDO) , AChR , AChE , Aurora Kinase
	1. Palmatine (Burasaine) is an inhibitor of dopamine generation. 2. Palmatine could potentially be developed for the treatment of flavivirus infections. 3. Palmatine has been used in the treatment of jaundice, dysentery,...
T25789	Melianone	NSC 302037,NSC-302037,NSC302037
	Melianone exhibits antiviral activity (EC50s: 3-11μM) against three important human pathogens, belonging to the Flaviviridae family, West Nile virus, Dengue virus, and Yellow Fever virus.
T72508	Palmatine hydroxide
	Palmatine hydroxide is an orally active, irreversible inhibitor of indoleamine 2,3-dioxygenase 1 (IDO-1), demonstrating IC50 values of 3 μM for HEK 293-hIDO-1 and 157μM for rhIDO-1. Additionally, it uncompetitively inhib...

天然物製品

Palmatine chloride

T2718

Synonym:

Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase

Palmatine

T5S0802

Synonym: Berbericinine,Burasaine

Target: Indoleamine 2,3-Dioxygenase (IDO), AChR, AChE, Aurora Kinase

Melianone

T25789

Synonym: NSC 302037,NSC-302037,NSC302037

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04735	West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein (His)	WNV	HEK293
	West Nile Virus (WNV) (lineage 1, strain NY99) NS1 Protein (His) is expressed in HEK293 with His tag. The predicted molecular weight is 42.1 kDa. Accession number: YP_001527881.1
TMPY-04299	West Nile Virus (WNV) (lineage 1, strain NY99) E/Envelope Protein (His)	WNV	Yeast
	West Nile Virus (WNV) (lineage 1, strain NY99) E/Envelope Protein (His) is expressed in Yeast with His tag. The predicted molecular weight is 12.9 kDa. Accession number: ABA62343.1
TMPY-04787	West Nile Virus (WNV) (lineage 2, strain Nea Santa-Greece-2010) E/Envelope Protein (His)	WNV	Yeast
	West Nile Virus (WNV) (lineage 2, strain Nea Santa-Greece-2010) E/Envelope Protein (His) is expressed in Yeast with His tag. The predicted molecular weight is 12.9 kDa. Accession number: AED99787.1
TMPY-02841	Fragilis/IFITM3 Protein, Human, Recombinant (mFc)	Human	HEK293
	Interferon-induced transmembrane protein 3 (IFITM3) belongs to the CD225 family. To replicate, viruses must gain access to the host cell's resources. Interferon (IFN) regulates the actions of a large complement of interf...
TMPH-01619	LY6E Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	GPI-anchored cell surface protein that regulates T-lymphocytes proliferation, differentiation, and activation. Regulates the T-cell receptor (TCR) signaling by interacting with component CD3Z/CD247 at the plasma membrane...
TMPH-01554	IFIH1 Protein, Human, Recombinant (His)	Human	E. coli
	Innate immune receptor which acts as a cytoplasmic sensor of viral nucleic acids and plays a major role in sensing viral infection and in the activation of a cascade of antiviral responses including the induction of type...
TMPH-01555	IFITM1 Protein, Human, Recombinant (GST)	Human	E. coli
	IFN-induced antiviral protein which inhibits the entry of viruses to the host cell cytoplasm, permitting endocytosis, but preventing subsequent viral fusion and release of viral contents into the cytosol. Active against ...